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Scientist II, Pharmaceutical Sciences

Beam Therapeutics

Beam Therapeutics

Cambridge, MA, USA
Posted on Thursday, May 11, 2023

Primary Responsibilities:

  • Dedicated to using innovative, biochemical science to conceive and develop precision, genetic medicines and novel solutions for fighting and treating serious diseases, other damaging medical conditions, and providing life-long cures (via professional-level scientist role in biochemistry, one of highly-scientific quality or character).
  • Contribute to use of groundbreaking, CRISPR base-editing technology that allows permanent, specific edits to single bases in DNA and RNA.
  • Develop base-editor therapeutics that represent a new class of “precision genetic medicines”, combining precision targeting of the genome with precision control of editing outcomes.
  • Contribute to new medicinal and scientific breakthrough, performing pharmaceutical design and development, all to ultimately give rise to therapeutically-beneficial, novel and innovative, drug product.
  • Contribute to the development and optimization of a biochemistry protocol for messenger-RNA purification.
  • Design and execute biochemistry strategies, contributing to the production of novel, therapy products in biochemistry and pharmaceutical science.
  • Engage in scientific knowledge transfer, regarding therapy product portfolio, this from the standpoint of biochemist and researcher.
  • Work with cross-functional team and interface with internal collaborators, specifically to troubleshoot in biochemistry.
  • Generate and optimize protocols around new scientific methods, specific to biochemistry and pharmaceutical science again.
  • Contribute to the development and optimization of new scientific processes, specific to those same areas as well.
  • Contribute to the writing and development of standard-operating procedures, used at Beam, as a way to optimize scientific protocols as a team.
  • Contribute biochemistry knowledge to the writing and development of detailed, highly-analytical, and professional, scientific reports (this to inform internal team discussions), while also communicating scientifically-rigorous findings verbally, by way of visualizations, and through presentations.
  • Perform biochemical testing, focused on pharmaceutical candidates equipped to treat.
  • Compile, analyze, interpret, and communicate complex, experimental results and other complex, biochemical data, drawing conclusions from these, this to identify and prioritize research targets.
  • Contribute research support to senior-level team members.
  • Capture and document research findings and results in a technically-accurate, scientifically-integral and understandable manner.
  • Stay current on relevant and occupationally-appropriate, scientific literature, notably regarding biochemistry.

Qualifications:

  • Doctor of Philosophy or foreign equivalent in biochemistry, chemistry, pharmaceutical sciences, biotechnology, or related field.
  • Also requires demonstrated proficiency in all of the following areas, shown through appropriate, graduate-level coursework, research or lab work:
    • Performing laboratory-based, biochemistry experiments, to include nanoparticle processing, working with nucleic acids, and using CRISPR cas9 methods.
    • Applying biophysical-characterization techniques that specifically include dynamic-light scattering, nitrilotriacetic-acid purification, high-performance liquid chromatography, capillary electrophoresis, and cryo-electron microscopy.

Other Information:

  • Permanent, full-time, immediately available, job opportunity.
  • Does not require travel (as role is substantially laboratory-based, in-house).
  • Primary worksite long-term: 238 Main Street, Cambridge, MA 02142.
  • Must therefore live in the City of Cambridge, MA, or within a reasonable, daily commuting distance thereof (e.g., areas contemplated can include the City of Boston, the larger Greater Boston region, or Massachusetts’ MetroWest, North or South Shore communities).
  • Telecommuting (exclusively working remotely from home) is not permitted (also due to the laboratory-based nature of the work and role).
  • Position is not a supervisory capacity; it does not have subordinate, direct reports; nor does it manage other personnel.
  • Position is hands-on, individual contributor, responsible chiefly for biochemistry.

Applicants should send resumes directly to the employer. May simply apply below. We look forward to hearing from you. Come join the Beam Team!