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Sr Associate Scientist, Synthetic Biology

Strand Therapeutics

Strand Therapeutics

Boston, MA, USA
Posted on Thursday, August 10, 2023

Company Overview:

Strand Therapeutics is an early-stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. This collaboration led them to build their own mRNA “programming language,” creating the world’s first platform for mRNA smart therapies.

The founders and scientific advisors of Strand Therapeutics are made up of well-known and highly regarded individuals in both academia and the biotech industry. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts with an additional site based in Watertown, Massachusetts.

Become the next standout single strand!

Job Summary:

Strand is looking to build a team that understands the value of working at a start-up. Joining the company now means having vast opportunities to learn and grow including having the exposure to all aspects of building a company. We are looking for people who have the enthusiasm and motivation to be a highly contributing member of a small team. This opportunity will offer the employee the ability to work closely with the founding team, as well as to form close partnerships with team members during the development and formation of the company.

We are looking for a highly motivated and innovative candidate for the role of Associate Scientist of Synthetic Biology. Reporting to the Scientist of Synthetic Biology, the ideal candidate will have experience in molecular cloning, mammalian cell culture, cell-based assays and IVT. The candidate will be expected to work in an innovative, fast-paced, cross-collaborative biotech environment and contribute to multi-disciplinary team activities to advance our platform.

Primary Responsibilities:

  • Molecular cloning using techniques such as Gibson Assembly and Golden Gate Assembly.
  • Synthesis of RNA through in vitro transcription.
  • Mammalian cell culture and transfection of nucleic acids into cultured mammalian cells.
  • Cell-based assays and molecular biology assays with readouts such as multi-color flow cytometry, luciferase, ELISA, and qPCR.
  • Coordination with other team members to support the group's research activities in a fast-paced and collaborative environment.

Qualifications:

  • B.S. with at least 4-5 years of relevant experience or M.S. with at least 2-3 years of relevant experience in cell biology and/or molecular biology.
  • Experience with molecular cloning such as Gibson Assembly and/or Golden Gate Assembly required.
  • Prior experience handling RNA highly preferred; Experience with the synthesis of RNA through IVT is a plus.
  • Experience in flow cytometry required; Experience in FACS data analysis is a plus.
  • Mammalian cell manipulation using mRNA transfection and/or electroporation highly desired.
  • Experience with laboratory automation equipment highly desired.
  • Experience in cellular/molecular biology methods including qPCR, ddPCR, ELISA and Western Blot is a plus.
  • Strong collaboration and inter-personal skills.
  • Ability to multi-task and prioritize to meet important deadlines.

Strand offers a fast-paced, entrepreneurial, team-focused work environment. We also offer a top-notch benefits package (health, dental, life, vacation, 401k, and commuter) and work/ life integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet the company goals.

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Full-time

Salary: Commensurate with role and experience